Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | XBP1 | P17861 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4179945 | 1.00 | LMNA (0.57) | LMNAMAPTRAB9APKMSMN1; SMN2 | |
| SCHEMBL10940657 | 0.86 | MAPT (0.62) | LMNAMAPTRAB9APKMSMN1; SMN2 | |
| SCHEMBL2571669 | 0.74 | LMNA (0.54) | LMNAMAPTRAB9APKMSMN1; SMN2 | |
| SCHEMBL10383576 | 0.73 | RAB9A (0.57) | LMNAMAPTRAB9APKMSMN1; SMN2 | |
| SCHEMBL10383575 | 0.73 | RAB9A (0.57) | LMNAMAPTRAB9APKMSMN1; SMN2 | |
| SCHEMBL11150916 | 0.67 | ALDH1A1 (0.73) | LMNAMAPTRAB9APKMSMN1; SMN2 | |
| SCHEMBL11080873 | 0.67 | ALDH1A1 (0.73) | LMNAMAPTRAB9APKMSMN1; SMN2 | |
| SCHEMBL10944619 | 0.67 | MAPT (0.61) | LMNAMAPTRAB9APKMSMN1; SMN2 | |
| SCHEMBL8781989 | 0.66 | MAPT (0.77) | LMNAMAPTRAB9APKMSMN1; SMN2 | |
| SCHEMBL8781988 | 0.66 | MAPT (0.77) | LMNAMAPTRAB9APKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143410-A1 | Isoxazolines for Controlling Invertebrate Pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-06-04 | — | — | US | disclosed |
| EP-1965645-A2 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070606-A2 | ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143410-A1 | Isoxazolines for Controlling Invertebrate Pests | CBR3, RTN3, HCN3 | LMNA 3367/4885MAPT 4883/4885RAB9A 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.