Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4345607 | 0.87 | ALDH1A1 (0.76) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9831153 | 0.85 | HSD11B1 (0.73) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL2747473 | 0.78 | HSD11B1 (1.00) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL10940832 | 0.74 | HSD11B1 (0.63) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL18912380 | 0.74 | HSD11B1 (0.81) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL25412127 | 0.72 | NPC1 (0.56) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL13984002 | 0.72 | KDM4E (0.61) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL30147353 | 0.72 | HSD11B1 (0.61) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL10939819 | 0.71 | HSD11B1 (0.65) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL2748146 | 0.71 | HSD11B1 (0.82) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036711-B1 | PESTICIDAL HETEROCYCLIC COMPOUNDS, PROCESSES FOR PREPARING THEM, COMPOSITIONS CONTAINING THEM, AND THEIR USE | FBC LIMITED (GB) | 1985-12-04 | — | — | EP | disclosed |
| US-4414221-A | MITICIDES, INSECTICIDES, APHIDICIDES | FBC LIMITED (GB) | 1983-11-08 | — | — | US | disclosed |
| EP-0036711-A2 | Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use | FBC LIMITED (GB) | 1981-09-30 | — | — | EP | disclosed |