Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940995 | 0.83 | MEN1 (0.46) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| 1,4-Butanediol SCHEMBL867061 | 0.81 | L3MBTL1 (0.35) | TSHRMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL461303 | 0.77 | L3MBTL1 (0.30) | L3MBTL1 | |
| SCHEMBL1073224 | 0.76 | — | — | |
| Di(Hydroxyethyl)Ether SCHEMBL20579713 | 0.75 | TSHR (0.62) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL28838448 | 0.75 | TSHR (0.62) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL29046448 | 0.72 | MEN1 (0.44) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL81016 | 0.72 | TSHR (0.59) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL19743240 | 0.72 | TSHR (0.59) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Triethylene Glycol SCHEMBL4448069 | 0.72 | MEN1 (0.65) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536206-A | CROSSLINKED HIGH MOLECULAR WEIGHT CARBOXYLIC CONTAINING POLYMER AND WATER, NONPHYTOTOXIC, NONTOXIC | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1985-08-20 | — | — | US | disclosed |