1,4-Butanediol

1,4-Butanediol

SCHEMBL867061

C=CC(C)(C)OC(C)(C)C=C.OCCCCO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.32
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL10940992 0.81 TSHR (0.46) L3MBTL1ALDH1A1MEN1KMT2ATSHR
SCHEMBL461303 0.81 L3MBTL1 (0.30) L3MBTL1
SCHEMBL867062 0.79 CYP4F2 (0.40) L3MBTL1CYP4F2CYP4A11
SCHEMBL27277315 0.76 CYP4F2 (0.33) L3MBTL1CYP4F2CYP4A11
SCHEMBL27856493 0.72
SCHEMBL1073224 0.70
SCHEMBL11375964 0.70 MEN1 (0.35) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
SCHEMBL10612243 0.70
1,4-Butanediol SCHEMBL565263 0.68 SMN1; SMN2 (0.47) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1
1,4-Butanediol SCHEMBL6334524 0.68 SMN1; SMN2 (0.47) SMN1; SMN2LMNAALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3131396-B1 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS BASF SE (DE) 2021-09-15 EP disclosed
US-10039281-B2 Pesticidal tape for controlling crawling pests BASF SE (DE) 2018-08-07 US disclosed
US-20170238538-A9 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS BASF SE (DE) 2017-08-24 US disclosed
US-20170035047-A1 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS BASF SE (DE) 2017-02-09 US disclosed
US-9464456-B2 System for protecting stored goods BASF SE (DE) 2016-10-11 US disclosed
EP-2723156-B1 SYSTEM FOR PROTECTING STORED GOODS BASF SE (DE) 2015-06-24 EP disclosed
US-20140190538-A1 System for Protecting Stored Goods BASF SE (DE) 2014-07-10 US disclosed
US-20120328685-A1 SYSTEM FOR PROTECTING GOODS DURING TRANSPORT BASF SE (DE) 2012-12-27 US disclosed
US-20120114727-A1 INSECTICIDAL SHEET-LIKE STRUCTURE FOR PROTECTING HUMANS AND DOMESTIC ANIMALS BASF SE (DE) 2012-05-10 US disclosed
US-20120114726-A1 INSECTICIDE-COATED SUBSTRATE FOR PROTECTING HUMANS AND PETS BASF SE (DE) 2012-05-10 US disclosed
US-20120079625-A1 Method for protecting living plants from harmful insects via a sheetlike structure BASF SE (DE) 2012-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170035047-A1 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS ACHE, AS3MT, DDT L3MBTL1 30/4885SMN1; SMN2 1033/4885LMNA 2638/4885
US-20120114727-A1 INSECTICIDAL SHEET-LIKE STRUCTURE FOR PROTECTING HUMANS AND DOMESTIC ANIMALS L3MBTL4, L3MBTL3, L3MBTL1 L3MBTL1 3/4885SMN1; SMN2 2198/4885LMNA 1829/4885
US-10039281-B2 Pesticidal tape for controlling crawling pests ACHE, AS3MT, DDT L3MBTL1 30/4885SMN1; SMN2 1033/4885LMNA 2638/4885
US-20170238538-A9 PESTICIDAL TAPE FOR CONTROLLING CRAWLING PESTS ACHE, AS3MT, DDT L3MBTL1 30/4885SMN1; SMN2 1033/4885LMNA 2638/4885
US-20120114726-A1 INSECTICIDE-COATED SUBSTRATE FOR PROTECTING HUMANS AND PETS DDT, PIR, CYP3A43 L3MBTL1 64/4885SMN1; SMN2 4339/4885LMNA 4622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.