Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.66 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30090684 | 0.89 | SIGMAR1 (0.69) | SIGMAR1TMEM97MAOACHRM2MEN1 | |
| SCHEMBL7202711 | 0.84 | SIGMAR1 (0.57) | SIGMAR1TMEM97MAOACHRM2MEN1 | |
| SCHEMBL28241166 | 0.80 | MEN1 (0.61) | SIGMAR1TMEM97MAOACHRM2MEN1 | |
| SCHEMBL7202171 | 0.80 | MAOA (0.53) | SIGMAR1TMEM97MAOACHRM2MEN1 | |
| SCHEMBL7206733 | 0.80 | MAOA (0.53) | SIGMAR1TMEM97MAOACHRM2MEN1 | |
| SCHEMBL7207674 | 0.80 | MAOA (0.58) | SIGMAR1TMEM97MAOACHRM2 | |
| SCHEMBL17372404 | 0.79 | SIGMAR1 (1.00) | SIGMAR1TMEM97MAOACHRM2TDP1 | |
| SCHEMBL15303616 | 0.79 | APP (0.48) | SIGMAR1TMEM97CHRM2 | |
| SCHEMBL6164283 | 0.79 | MAOA (0.60) | SIGMAR1TMEM97MAOACHRM2MEN1 | |
| SCHEMBL7202285 | 0.79 | MAOA (0.61) | SIGMAR1TMEM97MAOACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500452-A | NOT SUBJECT TO ENZYME DEACTIVATION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-02-19 | — | — | US | disclosed |
| US-4472304-A | CARCINOSTATIC | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1984-09-18 | — | — | US | disclosed |