Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207674 | 0.95 | MAOA (0.58) | SIGMAR1TMEM97MAOAAPPCHRM2 | |
| SCHEMBL7206731 | 0.94 | MAOA (0.61) | SIGMAR1TMEM97MAOAAPPCHRM2 | |
| SCHEMBL7202285 | 0.94 | MAOA (0.61) | SIGMAR1TMEM97MAOAAPPCHRM2 | |
| SCHEMBL6164283 | 0.92 | MAOA (0.60) | SIGMAR1TMEM97MAOACHRM2MEN1 | |
| SCHEMBL2538898 | 0.90 | MEN1 (0.53) | SIGMAR1TMEM97MAOAAPPCHRM2 | |
| SCHEMBL9326853 | 0.89 | APP (0.56) | APPCHRM2MAOBHTR1AADRA2A | |
| SCHEMBL9185975 | 0.85 | SIGMAR1 (0.44) | SIGMAR1TMEM97MAOAAPPCHRM2 | |
| SCHEMBL10941196 | 0.84 | SIGMAR1 (0.66) | SIGMAR1TMEM97MAOACHRM2MEN1 | |
| SCHEMBL5985351 | 0.83 | MAOA (0.58) | SIGMAR1TMEM97MAOACHRM2MEN1 | |
| SCHEMBL17346065 | 0.83 | APP (0.48) | APPCHRM2MAOBHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030229037-A1 | Novel cationic amphiphiles | MASSING ULRICH (DE) | 2003-12-11 | — | — | US | disclosed |
| EP-1261620-A2 | CATIONIC AMPHIPHILES FOR USE IN NUCLEIC ACID TRANSFECTION | Roche Diagnostics Corporation (US) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001057064-A2 | CATIONIC AMPHIPHILES FOR USE IN NUCLEIC ACID TRANSFECTION | ROCHE DIAGNOSTICS CORPORATION (US) | 2001-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229037-A1 | Novel cationic amphiphiles | ABHD16A, APMAP, ABCB4 | SIGMAR1 2152/4885TMEM97 384/4885MAOA 3723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.