Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 15/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2747473 | 0.87 | HSD11B1 (1.00) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL18912380 | 0.81 | HSD11B1 (0.81) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL7454138 | 0.80 | HSD11B1 (0.47) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL24820549 | 0.79 | HSD11B1 (0.63) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL8628370 | 0.79 | HSD11B1 (0.46) | HSD11B1ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL1544072 | 0.79 | HSD11B1 (0.55) | HSD11B1 | |
| SCHEMBL2748146 | 0.79 | HSD11B1 (0.82) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL4345607 | 0.79 | ALDH1A1 (0.76) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL19549118 | 0.78 | HSD11B1 (0.54) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL29920332 | 0.78 | HSD11B1 (0.46) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036711-B1 | PESTICIDAL HETEROCYCLIC COMPOUNDS, PROCESSES FOR PREPARING THEM, COMPOSITIONS CONTAINING THEM, AND THEIR USE | FBC LIMITED (GB) | 1985-12-04 | — | — | EP | disclosed |
| US-4414221-A | MITICIDES, INSECTICIDES, APHIDICIDES | FBC LIMITED (GB) | 1983-11-08 | — | — | US | disclosed |
| EP-0036711-A2 | Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use | FBC LIMITED (GB) | 1981-09-30 | — | — | EP | disclosed |