Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINH1 | P50454 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592657 | 0.84 | SERPINH1 (0.32) | SERPINH1MAPK1TSHRCYP3A4TDP1 | |
| SCHEMBL10941771 | 0.78 | TDP1 (0.37) | MAPK1TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL12112007 | 0.73 | TSHR (0.41) | SERPINH1MAPK1TSHRCYP3A4TDP1 | |
| SCHEMBL24986047 | 0.72 | MAPK1 (0.39) | SERPINH1MAPK1TSHRCYP3A4TDP1 | |
| SCHEMBL3701799 | 0.69 | TDP1 (0.40) | MAPK1TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL12112005 | 0.67 | TSHR (0.38) | SERPINH1MAPK1TSHRCYP3A4TDP1 | |
| SCHEMBL11137137 | 0.67 | TDP1 (0.35) | MAPK1TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL3699085 | 0.66 | TDP1 (0.37) | MAPK1TSHRCYP3A4TDP1ALDH1A1 | |
| SCHEMBL15744968 | 0.66 | PPARG (0.39) | SERPINH1TSHRCYP3A4ALDH1A1MAPT | |
| SCHEMBL6387456 | 0.66 | LMNA (0.46) | TSHRCYP3A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499149-A | ADHESION; HEAT RESISTANCE; PROTECTIVE COATINGS; SEMICONDUCTORS; POLYIMIDES | M&T CHEMICALS INC. (US) | 1985-02-12 | — | — | US | disclosed |
| US-4480009-A | POLYIMIDE, POLYAMIDEIMIDE, OR POLY-HALF-AMIDE | M&T CHEMICALS INC. (US) | 1984-10-30 | — | — | US | disclosed |
| US-4395527-A | POLYIMIDES FROM AMINOPOLYSILOXANES | M & T CHEMICALS INC. (US) | 1983-07-26 | — | — | US | disclosed |
| EP-0054426-A2 | Improvements in or relating to siloxanes | M & T CHEMICALS, INC. (US) | 1982-06-23 | — | — | EP | disclosed |
| US-RE30677-E | Silicone containing bis-thioether aromatic amines | M&T CHEMICALS INC. (US) | 1981-07-14 | — | — | US | disclosed |
| US-4139547-A | Silicone containing bis-thioether aromatic amines | BERGSTON & ASSOCIATES, INC. (US) | 1979-02-13 | — | — | US | disclosed |