Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137137 | 0.85 | TDP1 (0.35) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL10942843 | 0.78 | SERPINH1 (0.33) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL3701799 | 0.73 | TDP1 (0.40) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL3699085 | 0.70 | TDP1 (0.37) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL10592657 | 0.67 | SERPINH1 (0.32) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL10596567 | 0.65 | TDP1 (0.38) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL4948726 | 0.64 | TDP1 (0.48) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL28290605 | 0.64 | TDP1 (0.48) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL27660883 | 0.64 | TDP1 (0.43) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL3713630 | 0.64 | TSHR (0.34) | TDP1TSHRMAPK1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499149-A | ADHESION; HEAT RESISTANCE; PROTECTIVE COATINGS; SEMICONDUCTORS; POLYIMIDES | M&T CHEMICALS INC. (US) | 1985-02-12 | — | — | US | disclosed |
| US-4480009-A | POLYIMIDE, POLYAMIDEIMIDE, OR POLY-HALF-AMIDE | M&T CHEMICALS INC. (US) | 1984-10-30 | — | — | US | disclosed |
| US-4395527-A | POLYIMIDES FROM AMINOPOLYSILOXANES | M & T CHEMICALS INC. (US) | 1983-07-26 | — | — | US | disclosed |
| EP-0054426-A2 | Improvements in or relating to siloxanes | M & T CHEMICALS, INC. (US) | 1982-06-23 | — | — | EP | disclosed |