Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | TTR | P02766 | 5/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942424 | 0.97 | NPC1 (0.59) | NPC1RAB9ATTRCASP3SENP8 | |
| SCHEMBL10941723 | 0.93 | NPC1 (0.51) | NPC1RAB9ATTRCASP3SENP8 | |
| SCHEMBL10948788 | 0.91 | NPC1 (0.48) | NPC1RAB9ATTRCASP3SENP8 | |
| SCHEMBL11367075 | 0.85 | TTR (0.50) | NPC1RAB9ATTRMAOAMEN1 | |
| SCHEMBL10882826 | 0.78 | NPC1 (1.00) | NPC1RAB9ATTRCASP3SENP8 | |
| SCHEMBL10946013 | 0.77 | KDM4E (0.55) | NPC1RAB9AMAOAMEN1KMT2A | |
| SCHEMBL10939979 | 0.77 | ALDH1A1 (0.50) | NPC1RAB9AMAOAMEN1KMT2A | |
| SCHEMBL11319692 | 0.77 | NPC1 (0.71) | NPC1RAB9ATTRCASP3SENP8 | |
| SCHEMBL17127029 | 0.76 | NPC1 (0.49) | NPC1RAB9ATTRCASP3SENP8 | |
| SCHEMBL1787556 | 0.76 | TTR (1.00) | NPC1RAB9ATTRMAOAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |