Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.52 |
| ▸ | PGR | P06401 | 8/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 3/20 | 0.52 |
| ▸ | SHBG | P04278 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 7/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942189 | 1.00 | NR3C1 (0.52) | NR3C1PGRCYP3A4LMNAABCB11 | |
| SCHEMBL10943593 | 0.90 | LMNA (0.66) | NR3C1PGRCYP3A4LMNAABCB11 | |
| SCHEMBL10941436 | 0.90 | LMNA (0.66) | NR3C1PGRCYP3A4LMNAABCB11 | |
| SCHEMBL10596978 | 0.86 | PGR (0.61) | NR3C1PGRCYP3A4LMNAABCB11 | |
| SCHEMBL10598834 | 0.86 | PGR (0.61) | NR3C1PGRCYP3A4LMNAABCB11 | |
| SCHEMBL10943430 | 0.86 | PGR (0.49) | NR3C1PGRCYP3A4LMNAABCB11 | |
| SCHEMBL10943306 | 0.86 | PGR (0.44) | NR3C1PGRCYP3A4LMNAABCB11 | |
| SCHEMBL10898204 | 0.86 | NR3C1 (0.52) | NR3C1PGRCYP3A4LMNAABCB11 | |
| SCHEMBL10947612 | 0.85 | PGR (0.41) | NR3C1PGRCYP3A4LMNAABCB11 | |
| SCHEMBL10943932 | 0.84 | PGR (0.51) | NR3C1PGRCYP3A4LMNAABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4557867-A | CONTRACEPTIVES | THE UPJOHN COMPANY (US) | 1985-12-10 | — | — | US | disclosed |
| EP-0145493-A2 | 11-Difluoromethyl and 11-fluoromethylene steroids | THE UPJOHN COMPANY (US) | 1985-06-19 | — | — | EP | disclosed |