Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.36 |
| ▸ | TUBB | P07437 | 2/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080739 | 0.87 | C1R (0.38) | C1RLMNAADRA2AADRA2CADRA1D | |
| SCHEMBL10938067 | 0.81 | NR1I2 (0.39) | C1RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11256388 | 0.80 | NPY5R (0.38) | C1RTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10936710 | 0.77 | C1R (0.43) | C1RLMNATUBB4ATUBBTUBA3C | |
| SCHEMBL10939179 | 0.76 | C1R (0.40) | C1RLMNATUBB4ATUBBTUBA3C | |
| SCHEMBL11082598 | 0.73 | TSHR (0.51) | C1RLRRK2KMT2AHDAC3HDAC1 | |
| SCHEMBL11392051 | 0.72 | LMNA (0.49) | LMNALRRK2MEN1KMT2ANPSR1 | |
| SCHEMBL11083592 | 0.71 | HDAC3 (0.40) | C1RLMNAADRA2AADRA2CADRA1D | |
| SCHEMBL10943031 | 0.71 | LCK (0.41) | GAALCK | |
| SCHEMBL11295583 | 0.70 | CRHR1 (0.33) | C1RLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446142-A | HYPOTENSIVE AGENTS | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-05-01 | — | — | US | claimed |
| EP-0044266-B1 | SUBSTITUTED 3,5-DIAMINO-1,2,4-OXADIAZOLES AND 3,5-DIAMINO-1,2,4-THIADIAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Beiersdorf Aktiengesellschaft (DE) | 1985-09-18 | — | — | EP | disclosed |
| US-4446142-A | HYPOTENSIVE AGENTS | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1984-05-01 | — | — | US | disclosed |
| EP-0044266-A2 | Substituted 3,5-diamino-1,2,4-oxadiazoles and 3,5-diamino-1,2,4-thiadiazoles, their preparation and pharmaceutical compositions containing them | Beiersdorf Aktiengesellschaft (DE) | 1982-01-20 | — | — | EP | disclosed |