Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10946641 | 0.86 | MAPT (0.46) | ALDH1A1POLBKMT2ASMN1; SMN2MAPT | |
| SCHEMBL10946612 | 0.86 | ALOX15 (0.43) | NPC1KMT2ASMN1; SMN2ALOX15MAPT | |
| SCHEMBL10944770 | 0.84 | TSHR (0.51) | ALDH1A1TP53SMN1; SMN2TSHRCASP1 | |
| SCHEMBL9826671 | 0.82 | ALOX15 (0.36) | ALDH1A1KDM4ENPC1TP53SMN1; SMN2 | |
| SCHEMBL10949592 | 0.82 | ALOX15 (0.43) | TP53ALOX15MAPT | |
| SCHEMBL10944696 | 0.81 | ALOX15 (0.42) | NPC1TP53KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL1017166 | 0.81 | ALOX15 (0.40) | ALDH1A1KDM4ENPC1TP53KMT2A | |
| SCHEMBL10945094 | 0.81 | MAPT (0.46) | POLBKMT2ASMN1; SMN2ALOX15MAPT | |
| SCHEMBL10948376 | 0.80 | NPC1 (0.43) | ALDH1A1KDM4ENPC1TP53POLB | |
| SCHEMBL1014139 | 0.79 | ALOX15 (0.40) | ALDH1A1KDM4EPOLBKMT2ACTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515620-A | PRE- AND POSTEMERGENCE HERBICIDES, PLANT GROWTH REGULATORS | CIBA GEIGY CORPORATION (US) | 1985-05-07 | — | — | US | disclosed |