SCHEMBL10945614

SCHEMBL10945614

CCC(C)N(C)c1ccc2c(c1)OC(=O)C2C

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IGLV6-57 P01721 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10945528 0.79 MAPT (0.39)
SCHEMBL10945698 0.76
SCHEMBL10945626 0.76 MAPT (0.40) IGLV6-57
SCHEMBL11058994 0.70 CRHBP (0.48)
SCHEMBL7783606 0.70 BRD4 (0.43)
SCHEMBL7778988 0.70 PTPN1 (0.38)
SCHEMBL6887995 0.69 ALDH1A1 (0.35)
SCHEMBL39602 0.68 ALDH1A1 (0.36)
SCHEMBL6251806 0.68 ALDH1A1 (0.46)
SCHEMBL18952097 0.68 ALDH1A1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0078240-A2 Lactones CIBA-GEIGY AG (CH) 1983-05-04 EP claimed
US-4514415-A ANALGESICS CIBA GEIGY CORPORATION (US) 1985-04-30 US disclosed
EP-0078240-A2 Lactones CIBA-GEIGY AG (CH) 1983-05-04 EP disclosed