Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945528 | 0.79 | MAPT (0.39) | MAPT | |
| SCHEMBL10951924 | 0.76 | — | — | |
| SCHEMBL10945614 | 0.76 | IGLV6-57 (0.30) | IGLV6-57 | |
| SCHEMBL28704297 | 0.73 | ALDH1A1 (0.36) | MAPTIGLV6-57 | |
| SCHEMBL11058994 | 0.70 | CRHBP (0.48) | — | |
| SCHEMBL7783606 | 0.70 | BRD4 (0.43) | MAPT | |
| SCHEMBL28704790 | 0.70 | ALDH1A1 (0.34) | MAPT | |
| SCHEMBL27650176 | 0.68 | HPGD (0.51) | MAPTTRPV1 | |
| SCHEMBL14149516 | 0.68 | ADRA2A (0.46) | MAPT | |
| SCHEMBL4130557 | 0.68 | MAPT (0.66) | MAPTTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4514415-A | ANALGESICS | CIBA GEIGY CORPORATION (US) | 1985-04-30 | — | — | US | disclosed |