Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945129 | 0.97 | L3MBTL1 (0.43) | SMN1; SMN2KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL10942665 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL10944369 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL10944246 | 0.82 | L3MBTL1 (0.44) | SMN1; SMN2KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL10942993 | 0.82 | L3MBTL1 (0.44) | SMN1; SMN2KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL10944629 | 0.81 | ALDH1A1 (0.42) | SMN1; SMN2KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL10947566 | 0.79 | CACNA1F (0.42) | KMT2APOLBALDH1A1LMNACACNA1F | |
| SCHEMBL10942943 | 0.73 | L3MBTL1 (0.43) | SMN1; SMN2KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL10944724 | 0.71 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL10941388 | 0.69 | POLB (0.43) | SMN1; SMN2KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031104-B1 | THIAZOLIDINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-10-23 | — | — | EP | claimed |