Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943616 | 0.78 | KCNQ3 (0.40) | NPC1POLBNPSR1TAS1R3TAS1R1 | |
| SCHEMBL10946561 | 0.78 | NPC1 (0.44) | NPC1RAB9ANPSR1KCNQ3KCNQ2 | |
| SCHEMBL10660312 | 0.74 | TLR7 (0.47) | KDM4EPOLBNPSR1MAPTKCNQ3 | |
| SCHEMBL9839297 | 0.73 | TLR7 (0.46) | KDM4EPOLBNPSR1MAPTKCNQ3 | |
| SCHEMBL10660806 | 0.73 | RECQL (0.46) | NPC1RAB9ANPSR1TAS1R3TAS1R1 | |
| SCHEMBL9839295 | 0.72 | HTT (0.48) | NPC1RAB9AKDM4EALDH1A1NPSR1 | |
| SCHEMBL10665055 | 0.72 | CYP1A2 (0.46) | NPC1RAB9ANPSR1TAS1R3TAS1R1 | |
| SCHEMBL10945760 | 0.69 | NPC1 (0.43) | NPC1RAB9ANPSR1KCNQ3KCNQ2 | |
| SCHEMBL10660923 | 0.69 | NPC1 (0.44) | NPC1RAB9AALDH1A1TLR7MEN1 | |
| SCHEMBL9817951 | 0.68 | SMN1; SMN2 (0.60) | NPC1RAB9AKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518775-A | Benzoxazine-4-one intermediates | ROUSSEL UCLAF (FR) | 1985-05-21 | — | — | US | disclosed |
| US-4397856-A | Analgesic 4-hydroxy-3-quinolinecarboxamides | ROUSSEL UCLAF (FR) | 1983-08-09 | — | — | US | disclosed |