Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.43 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10660806 | 0.92 | RECQL (0.46) | NPC1RAB9ATP53HTTL3MBTL1 | |
| SCHEMBL9839295 | 0.91 | HTT (0.48) | NPC1RAB9ATP53HTTL3MBTL1 | |
| SCHEMBL10945760 | 0.90 | NPC1 (0.43) | NPC1RAB9ATP53HTTL3MBTL1 | |
| SCHEMBL10665055 | 0.90 | CYP1A2 (0.46) | NPC1RAB9ATP53HTTL3MBTL1 | |
| SCHEMBL10660923 | 0.90 | NPC1 (0.44) | NPC1RAB9ATP53HTTL3MBTL1 | |
| SCHEMBL10665884 | 0.86 | SMN1; SMN2 (0.46) | NPC1RAB9ATP53HTTL3MBTL1 | |
| SCHEMBL10943616 | 0.80 | KCNQ3 (0.40) | NPC1NPSR1TLR7KCNQ3KCNQ2 | |
| SCHEMBL10665753 | 0.79 | HTT (0.49) | NPC1RAB9ATP53HTTL3MBTL1 | |
| SCHEMBL10946169 | 0.78 | NPC1 (0.48) | NPC1RAB9ANPSR1MEN1KMT2A | |
| SCHEMBL10665904 | 0.76 | HSPA5 (0.60) | NPC1RAB9ATP53HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518775-A | Benzoxazine-4-one intermediates | ROUSSEL UCLAF (FR) | 1985-05-21 | — | — | US | disclosed |
| US-4397856-A | Analgesic 4-hydroxy-3-quinolinecarboxamides | ROUSSEL UCLAF (FR) | 1983-08-09 | — | — | US | disclosed |