Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10946561 | 0.80 | NPC1 (0.44) | KCNQ3KCNQ2KCNE1KCNQ1TLR7 | |
| SCHEMBL10946169 | 0.78 | NPC1 (0.48) | KCNQ3KCNQ2KCNE1KCNQ1TLR7 | |
| SCHEMBL10660312 | 0.74 | TLR7 (0.47) | KCNQ3KCNQ2KCNE1KCNQ1TLR7 | |
| SCHEMBL9839297 | 0.73 | TLR7 (0.46) | KCNQ3KCNQ2KCNE1KCNQ1TLR7 | |
| SCHEMBL10660806 | 0.72 | RECQL (0.46) | NPSR1TAS1R3TAS1R1NPC1FFAR2 | |
| SCHEMBL9839295 | 0.71 | HTT (0.48) | NPSR1TSHRHSD17B10NPC1FFAR2 | |
| SCHEMBL10665055 | 0.71 | CYP1A2 (0.46) | NPSR1TAS1R3TAS1R1NPC1FFAR2 | |
| SCHEMBL10945760 | 0.71 | NPC1 (0.43) | KCNQ3KCNQ2KCNE1KCNQ1TLR7 | |
| SCHEMBL10660923 | 0.71 | NPC1 (0.44) | TLR7CES2TSHRHSD17B10NPC1 | |
| SCHEMBL28669423 | 0.69 | CES2 (0.65) | KCNQ3KCNQ2KCNE1KCNQ1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518775-A | Benzoxazine-4-one intermediates | ROUSSEL UCLAF (FR) | 1985-05-21 | — | — | US | disclosed |
| US-4397856-A | Analgesic 4-hydroxy-3-quinolinecarboxamides | ROUSSEL UCLAF (FR) | 1983-08-09 | — | — | US | disclosed |