Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944475 | 0.97 | IMPDH2 (0.46) | KIF11RAB9ANPC1GABRA1GABRG2 | |
| SCHEMBL10942850 | 0.93 | IMPDH2 (0.53) | KIF11RAB9ANPC1IMPDH2KDM4E | |
| SCHEMBL10942326 | 0.90 | IMPDH2 (0.56) | KIF11RAB9ANPC1IMPDH2KDM4E | |
| SCHEMBL10947835 | 0.83 | KIF11 (0.43) | KIF11RAB9ANPC1GABRA1GABRG2 | |
| SCHEMBL10945260 | 0.83 | KDM4E (0.43) | KIF11RAB9ANPC1GABRA1GABRG2 | |
| SCHEMBL10942675 | 0.80 | KDM4E (0.43) | KIF11RAB9ANPC1GABRA1GABRG2 | |
| SCHEMBL10943903 | 0.80 | IMPDH2 (0.43) | KIF11RAB9ANPC1GABRA1GABRG2 | |
| SCHEMBL10945207 | 0.78 | SMN1; SMN2 (0.49) | KIF11RAB9ANPC1APEX1KDM4E | |
| SCHEMBL10945548 | 0.77 | ALDH1A1 (0.50) | RAB9ANPC1IMPDH2KDM4EALDH1A1 | |
| SCHEMBL10947215 | 0.77 | IMPDH2 (0.50) | KIF11RAB9ANPC1IMPDH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |