Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30581249 | 0.79 | KDM4E (0.60) | ALDH1A1LMNARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29076186 | 0.79 | KDM4E (0.60) | ALDH1A1LMNARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL10940832 | 0.77 | HSD11B1 (0.63) | HSD11B1ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL10939819 | 0.74 | HSD11B1 (0.65) | HSD11B1ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL10940616 | 0.73 | ATM (0.44) | HSD11B1ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL4215779 | 0.72 | HSD11B1 (0.50) | HSD11B1ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL10945027 | 0.70 | HSD11B1 (0.58) | HSD11B1ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL19549118 | 0.70 | HSD11B1 (0.54) | HSD11B1ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL10940862 | 0.70 | ALDH1A1 (1.00) | HSD11B1ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL2747473 | 0.70 | HSD11B1 (1.00) | HSD11B1ALDH1A1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036711-B1 | PESTICIDAL HETEROCYCLIC COMPOUNDS, PROCESSES FOR PREPARING THEM, COMPOSITIONS CONTAINING THEM, AND THEIR USE | FBC LIMITED (GB) | 1985-12-04 | — | — | EP | disclosed |
| US-4414221-A | MITICIDES, INSECTICIDES, APHIDICIDES | FBC LIMITED (GB) | 1983-11-08 | — | — | US | disclosed |
| EP-0036711-A2 | Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use | FBC LIMITED (GB) | 1981-09-30 | — | — | EP | disclosed |