Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810942 | 0.83 | GAA (0.45) | GAANPC1CD44TUBB4ATUBB | |
| SCHEMBL10946322 | 0.82 | GAA (0.48) | GAANPC1CD44TUBB4ATUBB | |
| SCHEMBL29749746 | 0.78 | CYP3A4 (0.50) | GAANPC1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL481060 | 0.78 | CYP3A4 (0.50) | GAANPC1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL8033045 | 0.77 | GAA (0.48) | GAANPC1CD44TUBB4ATUBB | |
| SCHEMBL28412705 | 0.76 | GAA (0.47) | GAANPC1CD44TUBB4ATUBB | |
| Hydrochloric Acid SCHEMBL9461963 | 0.76 | GAA (0.47) | GAANPC1CD44TUBB4ATUBB | |
| Hydrochloric Acid SCHEMBL9792949 | 0.76 | GAA (0.47) | GAANPC1CD44TUBB4ATUBB | |
| SCHEMBL6288225 | 0.74 | ACHE (0.46) | GAANPC1TUBB4ATUBBTUBA3C | |
| SCHEMBL6811706 | 0.74 | GAA (0.45) | GAANPC1CD44TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4085141-A | Process for the preparation of anilines meta-substituted by chlorine | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-18 | — | — | US | claimed |
| EP-0069907-B1 | PROCESS FOR PREPARING M-CHLORO-SUBSTITUTED ANILINES | BAYER AG (DE) | 1985-08-28 | — | — | EP | disclosed |
| US-4532350-A | Process for the selective preparation of meta-chloroanilines | RHONE-POULENC AGROCHIMIE (FR) | 1985-07-30 | — | — | US | disclosed |
| US-4495368-A | Process for the preparation of meta-halogenoanilines | RHONE-POULENC AGROCHIMIE (FR) | 1985-01-22 | — | — | US | disclosed |
| US-4460788-A | Process for preparation of anilines which are m-substituted by chlorine | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-17 | — | — | US | disclosed |
| EP-0051782-B1 | PROCESS FOR THE MANUFACTURE OF M-HALOGENATED ANILINES | BAYER AG (DE) | 1984-05-23 | — | — | EP | disclosed |
| US-4429156-A | Process for the preparation of m-halogen-substituted anilines | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| US-4418213-A | HYDRODEHALOGENATION LEWIS ACID AND NOBLE METAL CATALYSTS | RHONE-POULENC AGROCHIMIE (FR) | 1983-11-29 | — | — | US | disclosed |
| EP-0069907-A2 | Process for preparing m-chloro-substituted anilines | BAYER AG (DE) | 1983-01-19 | — | — | EP | disclosed |
| US-4351959-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-09-28 | — | — | US | disclosed |
| US-4340759-A | Process for the preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-07-20 | — | — | US | disclosed |
| EP-0051782-A1 | Process for the manufacture of m-halogenated anilines | BAYER AG (DE) | 1982-05-19 | — | — | EP | disclosed |
| US-4324914-A | Process for preparation of anilines substituted by chlorine in the meta-position | RHONE-POULENC AGROCHIMIE (FR) | 1982-04-13 | — | — | US | disclosed |
| US-4193937-A | DECHLORINATION OF CHLOROANILINES, SELECTIVE HYDROGENATION CATALYSTS OF NOBLE METAL AND SULFUR | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-18 | — | — | US | disclosed |
| US-4085141-A | Process for the preparation of anilines meta-substituted by chlorine | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-18 | — | — | US | disclosed |