Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797180 | 0.76 | KMT2A (0.47) | KMT2AP2RX4BCHEACHEMEN1 | |
| SCHEMBL10732552 | 0.73 | KMT2A (0.49) | KMT2AP2RX4BCHEACHECDK2 | |
| SCHEMBL9666485 | 0.72 | KMT2A (0.43) | KMT2AP2RX4BCHEACHEMEN1 | |
| SCHEMBL15156770 | 0.70 | AADAT (0.36) | KMT2AMEN1POLBKDM4ELMNA | |
| SCHEMBL29620057 | 0.68 | AADAT (0.35) | KMT2AMEN1POLBKDM4ELMNA | |
| SCHEMBL8023047 | 0.66 | P2RX4 (0.63) | P2RX4BCHEACHE | |
| SCHEMBL1321593 | 0.65 | P2RX4 (0.57) | KMT2AP2RX4BCHEACHENPC1 | |
| SCHEMBL16131284 | 0.65 | P2RX4 (1.00) | KMT2AP2RX4BCHEACHEMEN1 | |
| SCHEMBL18485408 | 0.65 | ALDH1A1 (0.53) | KMT2AP2RX4ACHEPOLBKDM4E | |
| SCHEMBL21282131 | 0.65 | P2RX4 (0.51) | KMT2AP2RX4BCHEACHEHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503073-A | ANTIINFLAMMATORY, ANALGESIC, ANTICOAGULANT | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-03-05 | — | — | US | disclosed |