Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.35 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411210 | 0.78 | AADAT (0.36) | AADATIDO1NOTUMMEN1KMT2A | |
| SCHEMBL15156770 | 0.78 | AADAT (0.36) | AADATPARK7HDAC3HDAC4HDAC1 | |
| SCHEMBL9903242 | 0.76 | OPRM1 (0.44) | AADATNOTUMMEN1KMT2ATLR9 | |
| SCHEMBL28779734 | 0.68 | PARK7 (0.42) | AADATPARK7HDAC3HDAC4HDAC1 | |
| SCHEMBL10948460 | 0.68 | KMT2A (0.51) | MEN1KMT2AKDM4EPOLBHTT | |
| SCHEMBL7612610 | 0.68 | CDC25A (0.56) | MAPTALDH1A1GAAKDM4EPOLB | |
| SCHEMBL30829186 | 0.61 | MEN1 (0.35) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL30722969 | 0.60 | AADAT (0.35) | AADATMEN1KMT2ATLR9MAPT | |
| SCHEMBL22631177 | 0.58 | AADAT (0.58) | AADATHDAC4HDAC7HDAC5IDO1 | |
| SCHEMBL19926520 | 0.58 | MEN1 (0.42) | IDO1MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110240558-B | Novel synthesis method of Flindokalner racemate | 上海华理生物医药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-110240558-B | Novel synthesis method of Flindokalner racemate | 上海华理生物医药股份有限公司 | 2022-05-27 | — | — | CN | disclosed |