Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681181 | 0.98 | L3MBTL1 (0.50) | ALDH1A1SMN1; SMN2MAPK1TSHRRAD52 | |
| SCHEMBL10942867 | 0.94 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPK1TSHRRAD52 | |
| SCHEMBL29625805 | 0.92 | KDM4E (0.56) | ALDH1A1SMN1; SMN2MAPK1TSHRKDM4E | |
| SCHEMBL2961648 | 0.92 | KDM4E (0.56) | ALDH1A1SMN1; SMN2MAPK1TSHRKDM4E | |
| SCHEMBL10946587 | 0.92 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPK1TSHRRAD52 | |
| SCHEMBL4206450 | 0.88 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPK1TSHRL3MBTL1 | |
| SCHEMBL10943151 | 0.82 | KDM4E (0.40) | ALDH1A1SMN1; SMN2MAPK1TSHRKDM4E | |
| SCHEMBL10942167 | 0.81 | NPC1 (0.54) | ALDH1A1SMN1; SMN2MAPK1TSHRL3MBTL1 | |
| SCHEMBL9762349 | 0.81 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPK1TSHRKDM4E | |
| SCHEMBL11207792 | 0.80 | KDM4E (0.55) | ALDH1A1L3MBTL1KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496447-A | PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS AND FOR CURING PRINTING INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1985-01-29 | — | — | US | disclosed |
| US-4374984-A | Aromatic-aliphatic ketones useful as photoinitiators | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-02-22 | — | — | US | disclosed |