SCHEMBL10948879

SCHEMBL10948879

Cc1ccc(CC(c2ccsc2)c2ccsc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.40
PPARG P37231 2/20 0.38
PPARA Q07869 2/20 0.38
IDO1 P14902 2/20 0.35
TDO2 P48775 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
ALOX5 P09917 1/20 0.33
RET P07949 1/20 0.33
PSMB5 P28074 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A3 Q01959 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9106668 0.80 PPARG (0.54) PPARGPPARASMN1; SMN2ALOX5
SCHEMBL10489055 0.74 SLC6A2 (0.55) SMN1; SMN2PSMB5SLC6A2SLC6A3TAAR1
SCHEMBL4973916 0.72 SLC6A2 (0.53) SMN1; SMN2PSMB5SLC6A2SLC6A3CYP19A1
SCHEMBL23071502 0.70 SIGMAR1 (0.44) IDO1TDO2SLC6A2SLC6A3CYP2A6
SCHEMBL29938176 0.70 SLC6A2 (0.55) PPARGPPARASMN1; SMN2SLC6A2SLC6A3
SCHEMBL10888496 0.69 ESR1 (0.57) SLC6A2CYP1A2TAAR1
SCHEMBL20319209 0.69 ALDH1A1 (0.52) IDO1SMN1; SMN2SLC6A2SLC6A3CYP1A2
SCHEMBL20751464 0.68 IDH1 (0.46) IDO1CYP1A2CYP2A6TAAR1
SCHEMBL2053141 0.68 SLC6A2 (0.59) PDE4APPARGPPARASMN1; SMN2SLC6A2
SCHEMBL6954698 0.68 ADRB3 (0.44) IDO1TDO2SLC6A2SLC6A3CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE31803-E REACTION PRODUCT OF FATTY ACID ESTER AND ACRYLIC MONOMER WITH OXIRANE COMPOUND AND AMINE WYANDOTTE PAINT PRODUCTS COMPANY (US) 1985-01-15 US disclosed
US-RE31616-E Cathodic electrodeposition coating compositions containing diels-alder adducts Wyandotte Paint Products (US) 1984-06-26 US disclosed
US-4339368-A Cationic coating compositions containing nitrogen heterocyclic materials WYANDOTTE PAINT PRODUCTS COMPANY (US) 1982-07-13 US disclosed
US-4246087-A Process for cationic electrodeposition GROW GROUP, INC. (US) 1981-01-20 US disclosed
EP-0020679-A1 CATIONIC COATING COMPOSITIONS. WYANDOTTE PAINT PROD (US) 1981-01-07 EP disclosed
US-4231907-A GLYCIDYL ACRYLATE POLYMER REACTED WITH FATTY ACID AND AMINE GROW GROUP INC. (US) 1980-11-04 US disclosed
WO-1980001071-A1 CATIONIC COATING COMPOSITIONS GROW GROUP INC (US) 1980-05-29 WO disclosed
US-4186117-A Cathodic electrodeposition coating compositions containing diels-alder adducts GROW CHEMICAL CORP. (US) 1980-01-29 US disclosed
US-4155824-A ACRYLIC POLYMER CONTAINING OXIRANE GROUPS WHICH HAVE BEEN OPENED WITH A FATTY ACID AND AN AMINE GROW CHEMICAL CORP. (US) 1979-05-22 US disclosed
US-4148704-A ADHESION, CORROSION RESISTANCE, GLOSS GROW CHEMICAL CORP. (US) 1979-04-10 US disclosed