Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.54 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11334630 | 0.93 | MAPT (0.70) | MAPTKDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL11329121 | 0.87 | MAPT (0.70) | MAPTKDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL11337415 | 0.87 | MAPT (0.66) | MAPTKDM4EHPGDHSD17B10RAB9A | |
| Resorcinol SCHEMBL11334634 | 0.83 | NPC1 (0.59) | MAPTKDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL11327576 | 0.82 | MAPT (0.57) | MAPTKDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL11553318 | 0.81 | MAPT (0.75) | MAPTKDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL11337898 | 0.81 | MAPT (0.74) | MAPTKDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL3372495 | 0.78 | MAPT (1.00) | MAPTKDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL688991 | 0.77 | ESR1 (0.70) | MAPTMEN1KMT2AESR1ESR2 | |
| SCHEMBL11762065 | 0.77 | RAB9A (0.61) | MAPTKDM4EHPGDHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4524165-A | 1,4-CYCLOHEXANEDICARBOXYLIC ACID AND 1,4-CYCLOHEXANE DIOL MONOMERS; POLYALKYLENE GLCOLS; STABILIZER MIXTURE | EASTMAN KODAK COMPANY (US) | 1985-06-18 | — | — | US | disclosed |