Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11561230 | 0.88 | HDAC6 (0.46) | MAPTHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL11841332 | 0.87 | HPGD (0.59) | MAPTHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL11632988 | 0.86 | CYP2C19 (0.52) | MAPTHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL11844094 | 0.86 | PDK1 (0.49) | MAPTHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL11520960 | 0.85 | MAPT (0.52) | MAPTHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL11524628 | 0.85 | AOC3 (0.50) | MAPTHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL11520957 | 0.84 | MAPT (0.53) | MAPTHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL11526072 | 0.84 | MAPT (0.52) | MAPTHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL11524636 | 0.82 | ALDH1A1 (0.46) | MAPTHPGDRAB9AALDH1A1NPC1 | |
| SCHEMBL10948982 | 0.82 | MAPT (0.64) | MAPTHPGDRAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4265804-A | BENZOXAZOYLBENZOATES, OXADIAZOLE-2,5-DIBENZOATES, BENZOTRIAZOLES AND BENZOTRIAZOTRIAZOLES | EASTMAN KODAK COMPANY (US) | 1981-05-05 | — | — | US | claimed |
| US-4265804-A | BENZOXAZOYLBENZOATES, OXADIAZOLE-2,5-DIBENZOATES, BENZOTRIAZOLES AND BENZOTRIAZOTRIAZOLES | EASTMAN KODAK COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| US-3988295-A | Organic compositions stabilized with benzoxazole or oxadiazole compounds | EASTMAN KODAK COMPANY (US) | 1976-10-26 | — | — | US | disclosed |