Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10949638 | 0.90 | MAPT (0.43) | ALDH1A1LMNAALOX15NPSR1MAPT | |
| SCHEMBL10874528 | 0.88 | ALDH1A1 (0.46) | ALDH1A1LMNAALOX15NPSR1MAPT | |
| SCHEMBL10880898 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNAALOX15NPSR1MAPT | |
| SCHEMBL10879461 | 0.81 | MAPT (0.38) | ALDH1A1LMNANPSR1MAPTMEN1 | |
| SCHEMBL10879000 | 0.81 | MAPT (0.48) | ALDH1A1LMNAALOX15NPSR1MAPT | |
| SCHEMBL10877250 | 0.75 | ALDH1A1 (0.49) | ALDH1A1LMNAALOX15NPSR1MAPT | |
| SCHEMBL10877196 | 0.72 | ALDH1A1 (0.39) | ALDH1A1LMNANPSR1MAPTMEN1 | |
| SCHEMBL10877149 | 0.72 | TYMP (0.37) | ALDH1A1LMNANPSR1MAPTMEN1 | |
| SCHEMBL10950776 | 0.69 | PDE3B (0.45) | LMNAALOX15NPSR1MAPTMEN1 | |
| SCHEMBL11362408 | 0.69 | LMNA (0.45) | ALDH1A1LMNAALOX15NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4526981-A | [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1985-07-02 | — | — | US | disclosed |