Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.59 |
| ▸ | LDHA | P00338 | 5/20 | 0.56 |
| ▸ | LDHB | P07195 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10948798 | 0.88 | SMN1; SMN2 (0.65) | SMN1; SMN2LMNAGAAFNTAFNTB | |
| SCHEMBL10955012 | 0.86 | TACR1 (0.59) | TACR1LDHALDHBLMNAGAA | |
| SCHEMBL10956644 | 0.85 | GAA (0.74) | TACR1LDHALDHBSMN1; SMN2LMNA | |
| SCHEMBL10952227 | 0.84 | LMNA (0.72) | SMN1; SMN2LMNAGAAFNTAFNTB | |
| SCHEMBL10954657 | 0.82 | SMN1; SMN2 (0.66) | TACR1SMN1; SMN2LMNAGAAFNTA | |
| SCHEMBL10950719 | 0.81 | CA12 (0.58) | SMN1; SMN2LMNAGAAFNTAFNTB | |
| SCHEMBL10952111 | 0.81 | FNTA (0.65) | SMN1; SMN2LMNAGAAFNTAFNTB | |
| SCHEMBL10953466 | 0.81 | FNTA (0.65) | SMN1; SMN2LMNAGAAFNTAFNTB | |
| SCHEMBL10953663 | 0.80 | CA12 (0.57) | SMN1; SMN2LMNAGAAFNTAFNTB | |
| SCHEMBL4431819 | 0.80 | CYP2C19 (0.55) | TACR1CYP2C19CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536346-A | TREATMENT OF ATHEROSCLEROSIS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | claimed |
| EP-0124791-A1 | Aralkanamidophenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1984-11-14 | — | — | EP | claimed |