Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10986155 | 0.94 | MMP3 (0.46) | GSK3BMMP3NPC1SMN1; SMN2MAPT | |
| SCHEMBL10983494 | 0.93 | MMP3 (0.49) | GSK3BMMP3NPC1MAPTALDH1A1 | |
| SCHEMBL10982313 | 0.93 | MMP3 (0.49) | GSK3BMMP3NPC1MAPTALDH1A1 | |
| SCHEMBL10985231 | 0.93 | MMP3 (0.49) | GSK3BMMP3NPC1MAPTALDH1A1 | |
| SCHEMBL10955027 | 0.88 | MAPK8 (0.38) | GSK3BMMP3SMN1; SMN2LMNALIMK1 | |
| SCHEMBL11664173 | 0.86 | MMP3 (0.46) | GSK3BMMP3NPC1SMN1; SMN2MAPT | |
| SCHEMBL10954392 | 0.79 | — | — | |
| SCHEMBL11554819 | 0.78 | MMP3 (0.41) | GSK3BMMP3NPC1SMN1; SMN2MAPT | |
| SCHEMBL11509915 | 0.78 | SMN1; SMN2 (0.53) | GSK3BMMP3NPC1SMN1; SMN2MAPT | |
| SCHEMBL7488715 | 0.77 | ALDH1A1 (0.46) | GSK3BMMP3NPC1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536189-A | FUEL ADDITIVE FOR GASOHOL | TEXACO INC. (US) | 1985-08-20 | — | — | US | disclosed |
| US-4492793-A | Process for the production of 2-amino-5-mercapto-1,3,4-thiadiazole | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1985-01-08 | — | — | US | disclosed |