Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | DNM2 | P50570 | 3/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10985231 | 1.00 | MMP3 (0.49) | MMP3NPC1MAPTALDH1A1STAT1 | |
| SCHEMBL10982313 | 1.00 | MMP3 (0.49) | MMP3NPC1MAPTALDH1A1STAT1 | |
| SCHEMBL10986155 | 0.98 | MMP3 (0.46) | MMP3NPC1MAPTALDH1A1STAT1 | |
| SCHEMBL10950488 | 0.93 | GSK3B (0.40) | MMP3NPC1MAPTALDH1A1STAT1 | |
| SCHEMBL10955027 | 0.85 | MAPK8 (0.38) | MMP3ALDH1A1GSK3BKMT2AALPL | |
| SCHEMBL11507326 | 0.80 | MMP3 (0.50) | MMP3NPC1MAPTALDH1A1STAT1 | |
| SCHEMBL11510375 | 0.80 | MMP3 (0.50) | MMP3NPC1MAPTALDH1A1STAT1 | |
| SCHEMBL7491690 | 0.79 | ALDH1A1 (0.51) | MMP3NPC1MAPTALDH1A1STAT1 | |
| SCHEMBL11664173 | 0.78 | MMP3 (0.46) | MMP3NPC1MAPTALDH1A1STAT1 | |
| SCHEMBL10954392 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4492793-A | Process for the production of 2-amino-5-mercapto-1,3,4-thiadiazole | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1985-01-08 | — | — | US | disclosed |