Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.58 |
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | DRD3 | P35462 | 3/20 | 0.58 |
| ▸ | HTR2B | P41595 | 3/20 | 0.58 |
| ▸ | HRH1 | P35367 | 2/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | HTR7 | P34969 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10949429 | 0.99 | DRD2 (0.57) | DRD2HTR2ADRD3HTR2BHRH1 | |
| SCHEMBL10799633 | 0.79 | ADRA2A (0.49) | DRD2DRD3HTR1AHTR7KDM4E | |
| Hydrochloric Acid SCHEMBL10947135 | 0.78 | ADRA2A (0.45) | DRD2DRD3KDM4EHSD17B10MEN1 | |
| SCHEMBL10800854 | 0.78 | ADRA2A (0.48) | DRD2DRD3HTR1AHTR7MEN1 | |
| Hydrochloric Acid SCHEMBL10947161 | 0.78 | ADRA2A (0.48) | DRD2DRD3HTR1AHTR7KDM4E | |
| SCHEMBL11130852 | 0.77 | HTR1A (0.49) | HTR1AHTR7MEN1ADRA2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL10946429 | 0.77 | ADRA2A (0.48) | DRD2HTR2ADRD3HTR2BHRH1 | |
| SCHEMBL10801493 | 0.76 | ADRA2A (0.51) | DRD2DRD3KDM4EMEN1LMNA | |
| Hydrochloric Acid SCHEMBL10949363 | 0.76 | HTR1A (0.48) | HTR1AHTR7MEN1ADRA2ACYP2D6 | |
| SCHEMBL7147206 | 0.76 | DRD2 (0.65) | DRD2HTR2ADRD3HTR2BHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4547507-A | ANTIDEPRESSANTS | ROUSSEL UCLAF (FR) | 1985-10-15 | — | — | US | claimed |
| US-4547507-A | ANTIDEPRESSANTS | ROUSSEL UCLAF (FR) | 1985-10-15 | — | — | US | disclosed |