Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422641 | 0.76 | ALDH1A1 (0.41) | ALDH1A1TDP1POLBMAPTKDM4E | |
| SCHEMBL10810296 | 0.75 | MAPT (0.46) | ALDH1A1TDP1LMNAPIN1L3MBTL1 | |
| SCHEMBL10912192 | 0.75 | ALDH1A1 (0.38) | ALDH1A1LMNACYP1A2HNF4ASMN1; SMN2 | |
| SCHEMBL10912189 | 0.74 | CTSV (0.38) | ALDH1A1LMNACYP1A2HNF4ASMN1; SMN2 | |
| SCHEMBL10500841 | 0.71 | ALDH1A1 (0.42) | ALDH1A1LMNACYP1A2POLBMAPT | |
| SCHEMBL10500865 | 0.69 | ALDH1A1 (0.43) | ALDH1A1LMNACYP1A2HNF4APOLB | |
| SCHEMBL11048331 | 0.68 | PTGES (0.44) | TDP1LMNACHEK1MAPTKDM4E | |
| SCHEMBL5654021 | 0.67 | ALDH1A1 (0.49) | ALDH1A1TDP1LMNAL3MBTL1MCL1 | |
| SCHEMBL10815663 | 0.67 | MAPT (0.53) | ALDH1A1TDP1LMNAL3MBTL1CYP1A2 | |
| SCHEMBL10978581 | 0.67 | ALDH1A1 (0.51) | ALDH1A1TDP1LMNAL3MBTL1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4604390-A | FUNGICIDES, ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0170412-A1 | Benzoselenino[4,3,2-cd]indazole compounds, compositions comprising the compounds and processes for producing the compounds | WARNER-LAMBERT COMPANY (US) | 1986-02-05 | — | — | EP | disclosed |