SCHEMBL1095111

SCHEMBL1095111

O=C(O)CCP(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.46
NR4A2 P43354 1/20 0.45
FFAR1 O14842 3/20 0.43
HDAC3 O15379 2/20 0.43
HDAC4 P56524 2/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC7 Q8WUI4 2/20 0.43
HDAC2 Q92769 2/20 0.43
HDAC10 Q969S8 2/20 0.43
HDAC11 Q96DB2 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
HDAC9 Q9UKV0 2/20 0.43
HDAC5 Q9UQL6 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MAPK1 P28482 1/20 0.43
ADRA1A P35348 1/20 0.43
SLC6A3 Q01959 1/20 0.43
FABP4 P15090 3/20 0.42
FABP5 Q01469 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9517922 0.98 KEAP1 (0.45) KEAP1NR4A2FFAR1HDAC3HDAC4
SCHEMBL20976401 0.87 HDAC3 (0.50) KEAP1NR4A2FFAR1HDAC3HDAC4
SCHEMBL5709198 0.85 HDAC3 (0.50) KEAP1NR4A2HDAC3HDAC4HDAC1
SCHEMBL10728992 0.83 ALDH1A1 (0.50) KEAP1SMN1; SMN2ALDH1A1CYP1A2CYP2D6
SCHEMBL9858681 0.83 KDM4E (0.43) KEAP1NR4A2SMN1; SMN2MAPK1SLC6A3
SCHEMBL6227647 0.82 KEAP1 (0.46) KEAP1NR4A2FFAR1HDAC3HDAC4
SCHEMBL28457741 0.81 ALDH1A1 (0.33) KEAP1NR4A2FFAR1HDAC3HDAC4
SCHEMBL1723688 0.81 KEAP1 (0.33) KEAP1NR4A2FFAR1HDAC3HDAC4
SCHEMBL9517914 0.81 HDAC3 (0.44) KEAP1NR4A2HDAC3HDAC4HDAC1
SCHEMBL21574237 0.80 KEAP1 (0.45) KEAP1NR4A2FFAR1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119488608-A Engineering bispecific antibody coupling drug and preparation method and application thereof 上海药明合联生物技术有限公司 2025-02-21 CN claimed
CN-119213022-A Preparation method of antibody-drug conjugate 上海迈晋生物医药科技有限公司 2024-12-27 CN claimed
CN-117838879-B Preparation method for improving homogeneity of antibody-drug conjugate and application thereof 上海药明合联生物技术有限公司 2024-11-01 CN claimed
CN-117838879-A Preparation method for improving homogeneity of antibody-drug conjugate and application thereof 上海药明合联生物技术有限公司 2024-04-09 CN claimed
WO-2023222108-A1 METHOD FOR PREPARING ANTIBODY-DRUG CONJUGATE 上海迈晋生物医药科技有限公司 2023-11-23 WO claimed
CN-114433239-B Rhodium nanoparticle dispersion and preparation method and application thereof 中国石油化工股份有限公司 2023-10-31 CN claimed
CN-114433239-A Rhodium nanoparticle dispersion and preparation method and application thereof 中国石油化工股份有限公司 2022-05-06 CN claimed
WO-2014147188-A1 TEMPERATURE-RESPONSIVE CATALYSTS EVONIK INDUSTRIES AG (DE) 2014-09-25 WO claimed
EP-0694522-A2 Process for preparing arylacetic acid derivatives by carbonylation of arylmethylhalogenids HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-31 EP claimed
EP-0327743-B1 PROCEDURE FOR MANUFACTURING SHORT-CHAIN LINEAR ALPHA- OLEFINES FROM ETHYLENE NESTE OY (FI) 1993-01-20 EP claimed
EP-0327743-A1 Procedure for manufacturing short-chain linear alpha- olefines from ethylene NESTE OY (FI) 1989-08-16 EP claimed
US-4285575-A USING AN ELECTROCHROMIC ELECTROLYTE CONTAINING A CARBOXYLIC-CONTAINING COMPLEXING AGENT, A FERROUS SALT, A METAL SALT, AND A CHROMOGEN; DURABILITY CANON KABUSHIKI KAISHA (JP) 1981-08-25 US claimed
US-4212518-A ELECTROCHROMIC CELL CANON KABUSHIKI KAISHA (JP) 1980-07-15 US claimed
CN-119488608-A Engineering bispecific antibody coupling drug and preparation method and application thereof 上海药明合联生物技术有限公司 2025-02-21 CN disclosed
CN-115368224-B System device and method for preparing hexamethylenediamine from butadiene 北京化工大学 2025-01-21 CN disclosed
CN-119213022-A Preparation method of antibody-drug conjugate 上海迈晋生物医药科技有限公司 2024-12-27 CN disclosed
WO-1980001690-A1 CARBONYLATION PROCESS AND NOVEL TRANSITION METAL CATALYSTS EXXON RESEARCH ENGINEERING CO (US) 1980-08-21 WO disclosed
EP-0014239-A2 Preparation of tertiary 2-carboxyethyl- and carboxymethyl phosphines, their salts and their use CHEMISCHE WERKE HÜLS AG (DE) 1980-08-20 EP disclosed
US-4212518-A ELECTROCHROMIC CELL CANON KABUSHIKI KAISHA (JP) 1980-07-15 US disclosed
US-3959385-A OR ALDEHYDESOXO PROCESS, GROUP 8 CARBONYL COMPLEX CATALYST BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed