Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | IAPP | P10997 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095111 | 0.83 | KEAP1 (0.46) | ALDH1A1SMN1; SMN2LMNAMAPTKEAP1 | |
| Acetic Acid SCHEMBL30885078 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| Acetic Acid SCHEMBL1075968 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| Acetic Acid SCHEMBL9803960 | 0.83 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL28904095 | 0.81 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDLMNACES2 | |
| Acetic Acid SCHEMBL9296547 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL9517922 | 0.81 | KEAP1 (0.45) | ALDH1A1SMN1; SMN2LMNAMAPTKEAP1 | |
| SCHEMBL17570461 | 0.80 | HSD11B1 (0.42) | ALDH1A1HPGDSMN1; SMN2CES2CES1 | |
| Ethane SCHEMBL28508951 | 0.80 | KDM4E (0.41) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL9858681 | 0.79 | KDM4E (0.43) | KDM4ESMN1; SMN2LMNAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218227-B | Method for preparing aryl ketone derivative | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |
| US-20210253611-A1 | TETRA-NUCLEAR NEUTRAL COPPER (I) COMPLEXES WITH DIARYLPHOSPHINE LIGANDS | CLARIANT INTERNATIONAL LTD (CH) | 2021-08-19 | — | — | US | disclosed |
| US-20210159432-A1 | TETRA-NUCLEAR NEUTRAL COPPER (I) COMPLEXES | CLARIANT INTERNATIONAL LTD (CH) | 2021-05-27 | — | — | US | disclosed |
| WO-2019243583-A1 | TETRA-NUCLEAR NEUTRAL COPPER (I) COMPLEXES | CLARIANT PLASTICS & COATINGS LTD (CH) | 2019-12-26 | — | — | WO | disclosed |
| WO-2019243581-A1 | TETRA-NUCLEAR NEUTRAL COPPER (I) COMPLEXES WITH DIARYLPHOSPHINE LIGANDS | CLARIANT PLASTICS & COATINGS LTD (CH) | 2019-12-26 | — | — | WO | disclosed |
| US-20160067351-A1 | SPECIFIC SITES FOR MODIFYING ANTIBODIES TO MAKE IMMUNOCONJUGATES | NOVARTIS AG (CH) | 2016-03-10 | — | — | US | disclosed |
| US-8871916-B2 | Diaryl phosphine compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-10-28 | — | — | US | disclosed |
| US-20130203974-A1 | Preparation of Diazo and Diazonium Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-08-08 | — | — | US | disclosed |
| US-8350014-B2 | Preparation of diazo and diazonium compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-08 | — | — | US | disclosed |
| US-20100125132-A1 | PREPARATION OF DIAZO AND DIAZONIUM COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2010-05-20 | — | — | US | disclosed |
| US-4687874-A | Selective hydroformylation process using alkyl diaryl phosphine rhodium carbonyl hydride catalysts | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1987-08-18 | — | — | US | disclosed |
| US-4687866-A | Ligand exchange process for producing alkyl diaryl phosphine rhodium carbonyl hydrides | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1987-08-18 | — | — | US | disclosed |
| US-4668809-A | ALKYL DIARYLPHOSPHINE RHODIUM CARBONYL HYDRIDES, HYDROFORMYLATION, OLEFINS | EXXON RESEARCH AND ENGINEERING (US) | 1987-05-26 | — | — | US | disclosed |
| US-4595753-A | Nitrogen heterocycle substituted | EXXON RESEARCH AND ENGINEERING CO. (US) | 1986-06-17 | — | — | US | disclosed |
| EP-0024091-B1 | HYDROFORMYLATION PROCESS AND NOVEL TRANSITION METAL CATALYSTS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1985-04-03 | — | — | EP | disclosed |
| EP-0024091-A4 | HYDROFORMYLATION PROCESS AND NOVEL TRANSITION METAL CATALYSTS. | EXXON RESEARCH ENGINEERING CO (US) | 1981-07-16 | — | — | EP | disclosed |
| EP-0024091-A1 | HYDROFORMYLATION PROCESS AND NOVEL TRANSITION METAL CATALYSTS. | EXXON RESEARCH ENGINEERING CO (US) | 1981-02-25 | — | — | EP | disclosed |
| WO-1980001690-A1 | CARBONYLATION PROCESS AND NOVEL TRANSITION METAL CATALYSTS | EXXON RESEARCH ENGINEERING CO (US) | 1980-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100125132-A1 | PREPARATION OF DIAZO AND DIAZONIUM COMPOUNDS | TREH, TALDO1, LIPE | ALDH1A1 2593/4885KDM4E 794/4885HPGD 3391/4885 |
| US-20210253611-A1 | TETRA-NUCLEAR NEUTRAL COPPER (I) COMPLEXES WITH DIARYLPHOSPHINE LIGANDS | NPSR1, TACR1, HRH3 | ALDH1A1 381/4885KDM4E 4824/4885HPGD 745/4885 |
| US-20130203974-A1 | Preparation of Diazo and Diazonium Compounds | TREH, TALDO1, LIPE | ALDH1A1 2593/4885KDM4E 794/4885HPGD 3391/4885 |
| US-20210159432-A1 | TETRA-NUCLEAR NEUTRAL COPPER (I) COMPLEXES | NPY1R, TAAR1, CHRNA1 | ALDH1A1 659/4885KDM4E 4099/4885HPGD 3547/4885 |
| US-20160067351-A1 | SPECIFIC SITES FOR MODIFYING ANTIBODIES TO MAKE IMMUNOCONJUGATES | PTMS, FCGR2A, FCGR3B | ALDH1A1 3096/4885KDM4E 1479/4885HPGD 4490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.