Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048611 | 0.92 | TDP1 (0.56) | PDE7ATDP1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10955819 | 0.90 | TDP1 (0.44) | PDE7ATDP1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10955246 | 0.88 | PDE7A (0.41) | PDE7ATDP1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10860196 | 0.87 | PDE7A (0.54) | PDE7ATDP1MAPTSMN1; SMN2LMNA | |
| SCHEMBL11132074 | 0.85 | PDE7A (0.54) | PDE7ATDP1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10953054 | 0.81 | ALDH1A1 (0.48) | TDP1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL11000058 | 0.81 | PIN1 (0.40) | PDE7ATDP1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10956448 | 0.81 | PPARG (0.38) | PDE7ATDP1MAPTSMN1; SMN2LMNA | |
| SCHEMBL10853995 | 0.81 | TDP1 (0.60) | TDP1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL10855202 | 0.80 | TDP1 (0.48) | PDE7ATDP1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4509970-A | Substituted phenylphosphinyloxy- and phosphinylthio-iminocarboxylates useful for the control of weeds | ZOECON CORPORATION (US) | 1985-04-09 | — | — | US | disclosed |