SCHEMBL10952015

SCHEMBL10952015

CCCCCCCCCCc1ccc(NCC(=O)O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
S1PR1 P21453 4/20 0.58
THRA P10827 3/20 0.57
THRB P10828 3/20 0.57
SPHK1 Q9NYA1 3/20 0.55
S1PR3 Q99500 2/20 0.55
S1PR2 O95136 2/20 0.55
RARB P10826 4/20 0.54
MEN1 O00255 1/20 0.54
RARA P10276 1/20 0.54
MAPT P10636 1/20 0.54
MTOR P42345 1/20 0.54
KMT2A Q03164 1/20 0.54
HAO1 Q9UJM8 1/20 0.54
HSD17B10 Q99714 2/20 0.53
HPGD P15428 1/20 0.53
ESR1 P03372 2/20 0.51
ADRA2A P08913 2/20 0.51
ADORA3 P0DMS8 2/20 0.51
TACR2 P21452 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10956825 1.00 ALDH1A1 (0.60) ALDH1A1S1PR1THRATHRBSPHK1
SCHEMBL11428645 1.00 ALDH1A1 (0.60) ALDH1A1S1PR1THRATHRBSPHK1
SCHEMBL10951825 1.00 ALDH1A1 (0.60) ALDH1A1S1PR1THRATHRBSPHK1
SCHEMBL5513033 1.00 ALDH1A1 (0.60) ALDH1A1S1PR1THRATHRBSPHK1
SCHEMBL8633832 0.93 ALDH1A1 (0.61) ALDH1A1S1PR1THRATHRBRARB
SCHEMBL10952675 0.86 L3MBTL1 (0.50) ALDH1A1THRBHSD17B10HPGDKDM4E
SCHEMBL28033400 0.86 SPHK1 (0.57) THRATHRBSPHK1
SCHEMBL11072168 0.83 PLK1 (0.49) ALDH1A1S1PR1SLC6A3KDM4ELMNA
Heptane SCHEMBL28185767 0.83 EPHX1 (0.54) ALDH1A1MEN1KMT2A
SCHEMBL28369542 0.83 RARB (0.65) ALDH1A1THRATHRBSPHK1RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4492683-A Method for inhibiting the growth of fungi with phenyl glycine compounds BUFFALO COLOR CORPORATION (US) 1985-01-08 US claimed
US-4492683-A Method for inhibiting the growth of fungi with phenyl glycine compounds BUFFALO COLOR CORPORATION (US) 1985-01-08 US disclosed