SCHEMBL8633832

SCHEMBL8633832

CCCCc1ccc(NCC(=O)O)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
HPGD P15428 3/20 0.61
HSD17B10 Q99714 1/20 0.61
POLB P06746 1/20 0.55
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
TRPV1 Q8NER1 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
RARB P10826 1/20 0.51
PLK1 P53350 1/20 0.51
S1PR1 P21453 1/20 0.50
GAA P10253 1/20 0.50
THRA P10827 1/20 0.49
THRB P10828 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5513033 0.93 ALDH1A1 (0.60) ALDH1A1HPGDHSD17B10RARBS1PR1
SCHEMBL11428645 0.93 ALDH1A1 (0.60) ALDH1A1HPGDHSD17B10RARBS1PR1
SCHEMBL10952015 0.93 ALDH1A1 (0.60) ALDH1A1HPGDHSD17B10RARBS1PR1
SCHEMBL10951825 0.93 ALDH1A1 (0.60) ALDH1A1HPGDHSD17B10RARBS1PR1
SCHEMBL10956825 0.93 ALDH1A1 (0.60) ALDH1A1HPGDHSD17B10RARBS1PR1
SCHEMBL10952675 0.89 L3MBTL1 (0.50) ALDH1A1HPGDHSD17B10POLBPLK1
SCHEMBL14557270 0.84 FFAR1 (0.48) ALDH1A1HPGDHSD17B10SMN1; SMN2
SCHEMBL10955013 0.82 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10POLBRAB9A
SCHEMBL2019464 0.80 POLB (0.70) ALDH1A1HPGDHSD17B10POLBNPC1
SCHEMBL10952623 0.80 FFAR1 (0.49) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0458485-B1 Image forming layer FUJI PHOTO FILM CO LTD (JP) 1998-07-29 EP disclosed
US-5395733-A Unsaturated polymer layer that can be decarboxylated on exposure to light and sensitizers FUJI PHOTO FILM CO., LTD. (JP) 1995-03-07 US disclosed
EP-0458485-A2 Image forming layer Fuji Photo Film Co., Ltd. (JP) 1991-11-27 EP disclosed
US-4492683-A Method for inhibiting the growth of fungi with phenyl glycine compounds BUFFALO COLOR CORPORATION (US) 1985-01-08 US disclosed
US-4443474-A ANTICONVULSANT, ADMINISTERING BUFFALO COLOR CORPORATION (US) 1984-04-17 US disclosed