Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLCO2A1 | Q92959 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | PTGIR | P43119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118067 | 0.91 | PTGDR2 (0.41) | PTGDR2ALDH1A1SLCO2A1PTGER4PTGER3 | |
| SCHEMBL10951862 | 0.91 | PTGDR2 (0.41) | PTGDR2ALDH1A1SLCO2A1PTGER4PTGER3 | |
| SCHEMBL11208056 | 0.90 | ALDH1A1 (0.49) | PTGDR2ALDH1A1SLCO2A1PTGER4PTGER3 | |
| SCHEMBL11208078 | 0.90 | ALDH1A1 (0.49) | PTGDR2ALDH1A1SLCO2A1PTGER4PTGER3 | |
| SCHEMBL11112289 | 0.87 | PTGDR2 (0.40) | PTGDR2ALDH1A1SLCO2A1PTGER4PTGER3 | |
| SCHEMBL11112287 | 0.87 | PTGDR2 (0.40) | PTGDR2ALDH1A1SLCO2A1PTGER4PTGER3 | |
| SCHEMBL10953515 | 0.85 | PTGFR (0.37) | ALDH1A1SLCO2A1PTGER4PTGER3 | |
| SCHEMBL10952666 | 0.82 | ITGB1 (0.31) | PTGDR2ALDH1A1SLCO2A1 | |
| SCHEMBL10865234 | 0.81 | ALDH1A1 (0.55) | PTGDR2ALDH1A1SLCO2A1PTGER4PTGER3 | |
| SCHEMBL10703299 | 0.80 | PTGIR (0.34) | PTGER4PTGER3PTGER2PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562204-A | ANTITUMOR, ANTILEUKEMIA AGENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1985-12-31 | — | — | US | disclosed |
| EP-0099672-A2 | Trans-Delta 2-prostaglandin D derivatives, process for their preparation and compositions containing them | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-02-01 | — | — | EP | disclosed |