Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10952060 | 0.77 | MAPT (0.41) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL10954064 | 0.77 | MAPT (0.41) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL15698060 | 0.75 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL10952676 | 0.69 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL13668567 | 0.68 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL10954844 | 0.67 | MAPK1 (0.39) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL10949738 | 0.67 | MAPK1 (0.39) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL3624714 | 0.66 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL10409133 | 0.65 | MAPT (1.00) | ALDH1A1MAPTMEN1MAPK1BLM | |
| SCHEMBL13542836 | 0.64 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1MAPK1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4494547-A | 2H-isoindolediones, their synthesis and use as radiosensitizers | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 1985-01-22 | — | — | US | disclosed |