Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.46 |
| ▸ | GSR | P00390 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.44 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Aspartate SCHEMBL30290726 | 1.00 | GRIK1 (0.46) | GRIK1GRIK2GRM1GRM2GSR | |
| Aspartic Acid SCHEMBL10954257 | 1.00 | GRIK1 (0.46) | GRIK1GRIK2GRM1GRM2GSR | |
| Aspartic Acid SCHEMBL14742380 | 0.90 | GRIK1 (0.50) | GRIK1GRIK2GRM1GRM2GSR | |
| Aspartic Acid SCHEMBL14742381 | 0.90 | GRIK1 (0.50) | GRIK1GRIK2GRM1GRM2GSR | |
| Aspartic Acid SCHEMBL27966204 | 0.90 | GRIK1 (0.50) | GRIK1GRIK2GRM1GRM2GSR | |
| Aspartic Acid SCHEMBL6941414 | 0.90 | GRIK1 (0.50) | GRIK1GRIK2GRM1GRM2GSR | |
| D-Aspartate SCHEMBL145539 | 0.87 | — | — | |
| Aspartic Acid SCHEMBL1526976 | 0.87 | GRIK1 (0.56) | GRIK1GRIK2GRM1GRM2GSR | |
| Aspartic Acid SCHEMBL3231 | 0.87 | — | — | |
| Aspartic Acid SCHEMBL11065189 | 0.87 | GRIK1 (0.56) | GRIK1GRIK2GRM1GRM2GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135307-A | Carrier for cell delivery | 株式会社ITO | 2022-09-30 | — | — | CN | disclosed |
| CN-108779216-A | Copolymer, the thickener containing the copolymer and allotment have the cosmetics of the copolymer | 富士胶片和光纯药株式会社 | 2018-11-09 | — | — | CN | disclosed |
| CN-102858366-B | Liquid formulations containing stabilized antibodies | 中外制药株式会社 | 2016-11-09 | — | — | CN | disclosed |
| CN-105944099-A | SOLUTION PREPARATION CONTAINING STABILIZED ANTIBODY | 中外制药株式会社 | 2016-09-21 | — | — | CN | disclosed |
| US-4561911-A | CONTAINING AMINO ACID | NIPPON STEEL CORPORATION (JP) | 1985-12-31 | — | — | US | disclosed |