Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22864545 | 0.86 | POLB (0.62) | POLBL3MBTL1SCN5ANOTUMNR1H4 | |
| SCHEMBL14123260 | 0.77 | ATM (0.63) | POLBL3MBTL1NTRK1IGF1RFGFR1 | |
| SCHEMBL8185171 | 0.76 | L3MBTL1 (0.72) | POLBL3MBTL1SCN5ANOTUMNR1H4 | |
| SCHEMBL4922308 | 0.75 | L3MBTL1 (0.48) | POLBL3MBTL1NR1H4TDP2MEN1 | |
| SCHEMBL16657387 | 0.74 | L3MBTL1 (0.50) | POLBL3MBTL1SCN5ANTRK1TDP2 | |
| SCHEMBL4930459 | 0.74 | L3MBTL1 (0.49) | POLBL3MBTL1TDP2MEN1MAPT | |
| SCHEMBL4947302 | 0.74 | HSP90AA1 (0.56) | POLBL3MBTL1TDP2MEN1CYP1A2 | |
| SCHEMBL10955104 | 0.74 | POLB (0.53) | POLBL3MBTL1NTRK1IGF1RFGFR1 | |
| SCHEMBL9375353 | 0.73 | POLB (0.46) | POLBL3MBTL1SCN5ANTRK1IGF1R | |
| SCHEMBL9378690 | 0.73 | POLB (0.46) | POLBL3MBTL1SCN5ANTRK1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518761-A | Process for the preparation of mixed trimers from organic isocyanates, the mixed trimers obtained according to the process and the use thereof for the production of polyurethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1985-05-21 | — | — | US | disclosed |