SCHEMBL9375353

SCHEMBL9375353

O=c1[nH]c(-c2ccccc2)c(I)c(=O)n1-c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MAPT P10636 2/20 0.42
NTRK1 P04629 2/20 0.41
IGF1R P08069 2/20 0.41
FGFR1 P11362 2/20 0.41
NTRK2 Q16620 2/20 0.41
NTRK3 Q16288 1/20 0.41
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
OPRL1 P41146 1/20 0.36
SCN5A Q14524 1/20 0.36
NPC1 O15118 2/20 0.34
LMNA P02545 2/20 0.34
RAB9A P51151 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HCRTR1 O43613 1/20 0.34
HCRTR2 O43614 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9378690 0.88 POLB (0.46) POLBL3MBTL1MAPTNTRK1IGF1R
SCHEMBL9376251 0.84 POLB (0.44) POLBL3MBTL1MAPTNTRK1IGF1R
SCHEMBL9381430 0.83 POLB (0.43) POLBL3MBTL1MAPTNTRK1IGF1R
SCHEMBL10954922 0.73 POLB (0.63) POLBL3MBTL1MAPTNTRK1IGF1R
SCHEMBL9378704 0.73 POLB (0.42) POLBL3MBTL1MAPTNTRK1IGF1R
SCHEMBL10955104 0.72 POLB (0.53) POLBL3MBTL1MAPTNTRK1IGF1R
SCHEMBL22864545 0.70 POLB (0.62) POLBL3MBTL1MAPTSCN5AMEN1
SCHEMBL4654259 0.70 L3MBTL1 (0.44) POLBL3MBTL1MAPTNTRK1IGF1R
SCHEMBL22165883 0.69 POLB (0.43) POLBL3MBTL1MAPTPPARGSCN5A
SCHEMBL10815057 0.67 NTRK1 (0.50) L3MBTL1MAPTNTRK1IGF1RFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0438209-B1 Uracil derivatives and pesticides containing the same as active ingredient NISSAN CHEMICAL IND LTD (JP) 1994-09-21 EP claimed
EP-0438209-A1 Uracil derivatives and pesticides containing the same as active ingredient NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1991-07-24 EP claimed
EP-0438209-B1 Uracil derivatives and pesticides containing the same as active ingredient NISSAN CHEMICAL IND LTD (JP) 1994-09-21 EP disclosed
US-5116404-A URACIL DERIVATIVES AND PESTICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1992-05-26 US disclosed
EP-0438209-A1 Uracil derivatives and pesticides containing the same as active ingredient NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1991-07-24 EP disclosed