Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10953176 | 0.84 | MEN1 (0.37) | MEN1KMT2ACES2CES1LMNA | |
| SCHEMBL10954935 | 0.77 | LMNA (0.38) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10951240 | 0.75 | SMYD3 (0.50) | LMNAALDH1A1SMN1; SMN2GRM5LTA4H | |
| SCHEMBL10946376 | 0.75 | LMNA (0.40) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10952498 | 0.74 | PKM (0.36) | CES2CES1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL22691798 | 0.73 | DRD2 (0.37) | MEN1KMT2ATP53RAB9AMAPT | |
| SCHEMBL10949987 | 0.72 | HDAC3 (0.39) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7527765 | 0.72 | DRD2 (0.38) | MEN1KMT2ACES1RAB9AMAPT | |
| SCHEMBL9909635 | 0.70 | DRD2 (0.55) | RAB9AMAPTNPSR1 | |
| SCHEMBL10947561 | 0.69 | GRM5 (0.42) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503073-A | ANTIINFLAMMATORY, ANALGESIC, ANTICOAGULANT | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-03-05 | — | — | US | disclosed |