Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166805 | 0.81 | CHRNB2 (0.40) | SLC18A3CHRNB2SLC6A2CHRNB4CHRNA3 | |
| SCHEMBL28117469 | 0.77 | CHRNB2 (0.42) | SLC18A3OPRL1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL11823390 | 0.69 | SLC18A3 (0.46) | SLC18A3OPRL1SLC6A3KCNH2 | |
| SCHEMBL11831180 | 0.69 | SLC18A3 (0.46) | SLC18A3OPRL1SLC6A3KCNH2 | |
| SCHEMBL11466330 | 0.69 | SLC18A3 (0.46) | SLC18A3OPRL1SLC6A3KCNH2 | |
| SCHEMBL14337143 | 0.69 | OPRL1 (0.67) | OPRL1 | |
| SCHEMBL19381874 | 0.69 | ALDH1A1 (0.39) | OPRL1CHRNB2SLC6A2CHRNB4CHRNA3 | |
| SCHEMBL498014 | 0.69 | OPRM1 (0.50) | OPRL1MEN1KMT2A | |
| SCHEMBL23008143 | 0.68 | SLC18A3 (0.35) | SLC18A3OPRL1 | |
| SCHEMBL21479543 | 0.68 | SLC18A3 (0.35) | SLC18A3OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049543-B1 | PERFUME COMPOSITIONS AND PERFUMED MATERIALS AND ARTICLES, CONTAINING PHENYL-TETRAHYDROFURANS AS A FRAGRANCE | NAARDEN INTERNATIONAL N.V. (NL) | 1985-03-20 | — | — | EP | disclosed |
| US-4404127-A | SOAPS; CLEANING COMPOUNDS; COSMETICS; DETERGENTS; OXIDATION RESISTANCE | NAARDEN INTERNATIONAL N.V. (NL) | 1983-09-13 | — | — | US | disclosed |
| EP-0049543-A1 | Perfume compositions and perfumed materials and articles, containing phenyl-tetrahydrofurans as a fragrance | NAARDEN INTERNATIONAL N.V. (NL) | 1982-04-14 | — | — | EP | disclosed |
| EP-0049545-A1 | High-pressure mercury vapour discharge lamp | Koninklijke Philips Electronics N.V. (NL) | 1982-04-14 | — | — | EP | disclosed |