Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SELP | P16109 | 2/20 | 0.47 |
| ▸ | TLR4 | O00206 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LY96 | Q9Y6Y9 | 2/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10956036 | 1.00 | LMNA (0.65) | LMNAPOLBKMT2ASELPTLR4 | |
| SCHEMBL21058372 | 0.90 | LMNA (0.65) | LMNAPOLBKMT2ATSHRALDH1A1 | |
| SCHEMBL11014953 | 0.89 | POLB (0.57) | LMNAPOLBKMT2ASELPTSHR | |
| SCHEMBL11014956 | 0.89 | POLB (0.57) | LMNAPOLBKMT2ASELPTSHR | |
| SCHEMBL11080692 | 0.88 | POLB (0.58) | LMNAPOLBKMT2ASELPTSHR | |
| SCHEMBL11080688 | 0.88 | POLB (0.58) | LMNAPOLBKMT2ASELPTSHR | |
| SCHEMBL8931470 | 0.86 | POLB (0.79) | LMNAPOLBKMT2ATSHRALDH1A1 | |
| SCHEMBL21097453 | 0.86 | POLB (0.79) | LMNAPOLBKMT2ATSHRALDH1A1 | |
| SCHEMBL8931476 | 0.86 | POLB (0.79) | LMNAPOLBKMT2ATSHRALDH1A1 | |
| SCHEMBL20788116 | 0.85 | LMNA (0.61) | LMNAPOLBKMT2ATLR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4495346-A | CATALYTICALLY COUPLING TWO MONOSACCHARIDES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1985-01-22 | — | — | US | disclosed |