Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080692 | 1.00 | POLB (0.58) | POLBLMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL11014956 | 0.99 | POLB (0.57) | POLBLMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL11014953 | 0.99 | POLB (0.57) | POLBLMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL10956041 | 0.88 | LMNA (0.65) | POLBLMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL10956036 | 0.88 | LMNA (0.65) | POLBLMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL8931470 | 0.84 | POLB (0.79) | POLBLMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL21097453 | 0.84 | POLB (0.79) | POLBLMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL8931476 | 0.84 | POLB (0.79) | POLBLMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL21058372 | 0.83 | LMNA (0.65) | POLBLMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL6859193 | 0.82 | LMNA (0.62) | POLBLMNAKMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4495346-A | CATALYTICALLY COUPLING TWO MONOSACCHARIDES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1985-01-22 | — | — | US | disclosed |