Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507360 | 0.88 | CA12 (0.54) | CA12CA1CA9HDAC3HDAC1 | |
| SCHEMBL9989067 | 0.82 | MAOB (0.55) | CA12CA1CA9MAOBTAS1R3 | |
| SCHEMBL446971 | 0.81 | TAS1R3 (0.64) | CA12CA1CA9TAS1R3TAS1R1 | |
| SCHEMBL8700176 | 0.80 | TAS1R3 (0.50) | MAOBTAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL26041373 | 0.77 | CA1 (0.49) | CA12CA1CA9LMNAMAPT | |
| SCHEMBL8696625 | 0.77 | FLT3 (0.76) | CA12CA9MAOBTAS1R3TAS1R1 | |
| SCHEMBL445130 | 0.75 | KDM4E (0.55) | MAOBALDH1A1KDM4ETSHR | |
| SCHEMBL6042961 | 0.75 | MAPT (0.47) | CA12CA1CA9LMNAMAPT | |
| SCHEMBL9048693 | 0.74 | PIM1 (0.49) | MAOBTAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL5376581 | 0.74 | BLM (0.50) | CA12CA1CA9ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061800-B1 | ANTI SRS-A CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | FISONS plc (GB) | 1985-08-28 | — | — | EP | disclosed |
| US-4518612-A | Naphthalene and 2-oxo-benzopyran acids and derivatives and pharamaceutical use thereof | FISONS PLC (GB) | 1985-05-21 | — | — | US | disclosed |
| US-4424231-A | Compounds | FISONS LIMITED (GB) | 1984-01-03 | — | — | US | disclosed |
| EP-0061800-A1 | Anti SRS-A carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them | FISONS plc (GB) | 1982-10-06 | — | — | EP | disclosed |