SCHEMBL26041373

SCHEMBL26041373

C=CCOc1ccc2cc(C(=O)OC)ccc2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.49
MAPT P10636 3/20 0.49
CA12 O43570 3/20 0.49
CA9 Q16790 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
POLB P06746 1/20 0.49
BLM P54132 1/20 0.48
LMNA P02545 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
PTPN11 Q06124 1/20 0.48
CHRNB2 P17787 2/20 0.47
CHRNB4 P30926 2/20 0.47
CHRNA3 P32297 2/20 0.47
CHRNA4 P43681 2/20 0.47
HGFAC Q04756 1/20 0.47
ADRB2 P07550 2/20 0.46
ADRB1 P08588 2/20 0.46
ADRB3 P13945 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6042961 0.97 MAPT (0.47) CA1MAPTCA12CA9SMN1; SMN2
SCHEMBL9276612 0.88 PTPN1 (0.53) CA1MAPTCA12CA9SMN1; SMN2
SCHEMBL15927541 0.87 CA12 (0.50) CA1MAPTCA12CA9SMN1; SMN2
SCHEMBL542658 0.86 MAPT (0.66) CA1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL11046516 0.85 PTPN11 (0.54) CA1MAPTCA12CA9SMN1; SMN2
SCHEMBL758035 0.84 ADRB2 (0.61) SMN1; SMN2NPC1RAB9APOLBBLM
SCHEMBL10958710 0.83 MAPT (0.48) CA1MAPTCA12CA9SMN1; SMN2
SCHEMBL8327563 0.83 KDM4E (0.56) CA1MAPTCA12CA9SMN1; SMN2
SCHEMBL3879952 0.83 MAPT (0.71) CA1MAPTCA12CA9SMN1; SMN2
SCHEMBL8332709 0.82 MAPT (0.56) CA1MAPTCA12CA9SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023158223-A1 PERFLUOROPOLYETHER GROUP-BEARING SILANE COMPOUND AND COMPOSITION CONTAINING SAME FOR SURFACE TREATMENT 동우 화인켐 주식회사 2023-08-24 WO disclosed